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No Lumbar Puncture in the Evaluation for Early Neonatal Sepsis:Will Meningitis Be Missed? Pediatrics 95:803-806, Wiswell,T.E.,et al, 1995 See this aricle in Pubmed Article Abstract If we had used currently advocated selective criteria as the basis for not performing an LP,the diagnosis of bacterial meningitis would have been missed or delayed in 16 of 43 infants(37%);5 infants born prematurely with suspected respiratory distress syndrome,3 asymptomatic infants born at term with positive blood cultures,and 8 infants born at term with no central nervous system symptoms and negative blood cultures.If LPs are omitted as part of the early neonatal sepsis evaluation,the diagnosis of bacterial meningitis occasionally will be delayed or missed completely.

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